Ethyl glucuronide (EtG) is a direct metabolite of ethanol and is widely accepted as a reliable biomarker for the assessment of gestational consumption when measured in maternal hair and prenatal exposure to alcohol when mea-sured in neonatal meconium. It has been shown that maternal self-reports on drinking habits during pregnancy are misleading and unreliable for various reasons, including recall bias, shame, and/or fear of stigma. In this concern, the objective assessment of real alcohol consumption through the measurement of EtG is preferable.

. 2023 Jun;5(6):100944. doi: 10.1016/j.ajogmf.2023.100944. Epub 2023 Mar 25.

Nunzia La Maida¹, Alessandro Di Giorgi², Manuela Pellegrini¹, Mauro Ceccanti³, Salvatore Caruso⁴, Giuseppe Ricci⁵, Isabella Neri⁶, Sheherazade Lana⁷, Adele Minutillo¹, Paolo Berretta¹, Francesco Paolo Busardò², Simona Pichini⁸; CCM Study Group

Collaborators

CCM Study Group:
Franco Camandona, Lucia Vaccari, Laura Travan, Giampaolo Maso, Tamara Stampalija, Lucia Zanazzo, Paola Pisana, Lorenza Driul, Elisa Barbui, Claudia Caissutti, Elena Valente, Alba Ricchi, Elisa Bettiga, Elisa Piccolo, Mariangela Pati, Simona Pedori, Patrizio Antonazzo, Gilda Sottile, Fabrizio Lo Faro, Anastasio Tini, Mario Massacesi, Carmen Rapisarda, Gabriella Vivirito, Giampiero Pinna, Mariarosa D’anna, Lili Klein, Antonino Bucolo, Rosario D’Anna, Caterina Monaco, Giuseppe La Ferrera, Giampiero Capobianco, Mauro Giorgio Olzai, Stefano Angioni, Maurizio Nicola D’Alterio, Paolo Serravalle, Christine Vicquéry, Sabrina Scalchi, Carla Morando, Margherita Meneghin, Cinzia Scapolan, Tiziano Maggino, Barbara Guarinoni, Giovanna M Cristina Napolitano, Maria Grazia De Vita, Costantino Di Carlo, Fabiana Interlandi, Massimo Bisceglia, Michelangelo Barbaglia, Alberto Arnulfo, Enrico Finale, Luca Marozio, Ilaria Natali, Signoretti Maria Grazia, Alex Staffler, Luigi Tarani, Giovanna Coriale, Marisa Patrizia Messina, Alessio D’Angelo, Marco Bonito, Cristina Haass, Letizia Capasso, Francesco Raimondi, Giuseppe De Bernardo, Pietro Iacobelli, Simona Spadarella, Enrica Mastantuoni, Raffaello Rabuano, Francesco Calzatini, Anna Bossi, Salvatore Aversa, Federico Prefumo, Cristina Bellan, Giovanna Leone, Massimo Ciammella, Silvia Von-Wunster, Antonella Liguori, Sara Ornaghi, Simona Fumagalli, Fabio Sanguineti, Gaia Gianola, Angelo Cagnacci, Arianna Amidani, Antonio Sisto, Francesca Di Marcello, Vincenzo Santillo, Cristina Di Bartolomeo, Sandro Gerli, Giacomo Cagnoli, Mirella Petrisano, Simona Pesce, Nicola Di Lascio, Sonia Falvino, Petronilla Appio, Vincenza Targiani, Anna Franca Cavaliere, Irene Turrini, Gilda Belli, Beatrice Gambi, Pasquale Florio, Elena Degli Innocenti, Letizia Magi, Flavio Civitelli, Luigi Nappi, Felice Sorrentino, Teresa Silvestris, Flavia Indrio, Nicola Laforgia, Valentina Rizzo, Maria La Rocca, Ugo Pradal, Luigi Memo, Claudio Diaz, Patrizia Riscica, Stefania Bazz

Affiliations

¹National Centre on Addiction and Doping, Istituto Superiore di Sanità, Rome, Italy.
²Department of Excellence of Biomedical Science and Public Health, University “Politecnica delle Marche”, Ancona, Italy.
³Alcohol Addiction Program, Latium Region Referral Center, Sapienza University of Rome, Rome, Italy.
⁴Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
⁵Institute for Maternal and Child Health, IRCCS Burlo Galofaro, Trieste, Italy; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
⁶Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.
⁷Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.
⁸National Centre on Addiction and Doping, Istituto Superiore di Sanità, V. Le Regina Elena 299, 00161 Rome, Italy. Electronic address: simona.pichini@iss.it.

- PMID: 36972834

DOI: 10.1016/j.ajogmf.2023.100944

- PMID: 36972834

DOI: 10.1016/j.ajogmf.2023.100944

Reduced prevalence of fetal exposure to alcohol in Italy: a nationwide survey

Nunzia La Maida 1, Alessandro Di Giorgi 2, Manuela Pellegrini 1, Mauro Ceccanti 3, Salvatore Caruso 4, Giuseppe Ricci 5, Isabella Neri 6, Sheherazade Lana 7, Adele Minutillo 1, Paolo Berretta 1, Francesco Paolo Busardò 2, Simona Pichini 8; CCM Study Group

Affiliations

Nunzia La Maida¹, Alessandro Di Giorgi², Manuela Pellegrini¹, Mauro Ceccanti³, Salvatore Caruso⁴, Giuseppe Ricci⁵, Isabella Neri⁶, Sheherazade Lana⁷, Adele Minutillo¹, Paolo Berretta¹, Francesco Paolo Busardò², Simona Pichini⁸; CCM Study Group